{APPRIS}

Annotating principal splice isoforms


APPRIS Database currently houses annotations for vertebrate genomes »

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APPRIS Database currently houses annotations for invertebrate genomes »

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APPRIS

The APPRIS WebServer [1] executes a range of computational methods to annotate splice variants for individual genes. As part of its annotation process APPRIS selects a single CDS as the principal isoform for each gene.
The APPRIS Database [2] houses protein structure, function and conservation information for splice variants in five genomes.

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Publications

[1] APPRIS WebServer and WebServices. Rodriguez JM, et al.
Nucleic Acids Res. 2015 May 18.
PUBMED:25990727 DOI:10.1093/nar/gkv512
[2] APPRIS: annotation of principal and alternative splice isoforms. Rodriguez JM, et al.
Nucleic acids research 2013;41;Database issue;D110-7
PUBMED:23161672 PMC:3531113 DOI:10.1093/nar/gks1058

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API

The APPRIS Database and APPRIS WebServer can be accessed through a range of RESTful web services. These services can retrieve both gene/transcript information and the results of the individual APPRIS modules.

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